Papers (Neuron 1/6/5)

-NMDA Receptor-Dependent Activation of the Small GTPase Rab5 Drives the Removal of Synaptic AMPA Receptors during Hippocampal LTD (José Esteban's et al.) Neuron, Vol 45, 81-94

Congratulations, José ! It might be fun to see interactions between Rab5 and the C terminus of rabaptin-5 (last 74 amino acids) using our FLIM system.

-Dendritic Spine Heterogeneity Determines Afferent-Specific Hebbian Plasticity in the Amygdala (Andreas Lüthi et al.) Neuron, Vol 45, 119-131

It is always great to see a paper citing my paper! They identify spines connected by thalamic and cortical affarents by calcium imaging. These spines are functionally and morphologically distinct. it surprises me a bit that one can do this kind of experiment. Looking for a stimulated spine is difficult especially if one stimulates far from a patched neuron. It is a kind of needle-in-haystack problem: only a small fraction of spine is activated to show a rapid and stochastic (some times release probability is less than 0.1) calcium responses.